Does VALPROIC ACID Cause Acute hepatic failure? 99 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 99 reports of Acute hepatic failure have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.5% of all adverse event reports for VALPROIC ACID.
99
Reports of Acute hepatic failure with VALPROIC ACID
0.5%
of all VALPROIC ACID reports
22
Deaths
69
Hospitalizations
How Dangerous Is Acute hepatic failure From VALPROIC ACID?
Of the 99 reports, 22 (22.2%) resulted in death, 69 (69.7%) required hospitalization, and 18 (18.2%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 99 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which VALPROIC ACID Alternatives Have Lower Acute hepatic failure Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN