Does PYRAZINAMIDE Cause Acute hepatic failure? 170 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 170 reports of Acute hepatic failure have been filed in association with PYRAZINAMIDE (Pyrazinamide). This represents 3.1% of all adverse event reports for PYRAZINAMIDE.
170
Reports of Acute hepatic failure with PYRAZINAMIDE
3.1%
of all PYRAZINAMIDE reports
30
Deaths
117
Hospitalizations
How Dangerous Is Acute hepatic failure From PYRAZINAMIDE?
Of the 170 reports, 30 (17.6%) resulted in death, 117 (68.8%) required hospitalization, and 22 (12.9%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PYRAZINAMIDE. However, 170 reports have been filed with the FAERS database.
What Other Side Effects Does PYRAZINAMIDE Cause?
Drug-induced liver injury (588)
Drug reaction with eosinophilia and systemic symptoms (492)
Paradoxical drug reaction (407)
Vomiting (307)
Pyrexia (301)
Drug ineffective (298)
Off label use (288)
Hepatotoxicity (279)
Drug resistance (269)
Nausea (251)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which PYRAZINAMIDE Alternatives Have Lower Acute hepatic failure Risk?
PYRAZINAMIDE vs PYRIDOSTIGMINE
PYRAZINAMIDE vs PYRIDOXINE
PYRAZINAMIDE vs PYRIDOXINE\THIAMINE
PYRAZINAMIDE vs PYRIMETHAMINE
PYRAZINAMIDE vs PYROTINIB