Does PACLITAXEL Cause Acute hepatic failure? 139 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 139 reports of Acute hepatic failure have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.2% of all adverse event reports for PACLITAXEL.
139
Reports of Acute hepatic failure with PACLITAXEL
0.2%
of all PACLITAXEL reports
103
Deaths
96
Hospitalizations
How Dangerous Is Acute hepatic failure From PACLITAXEL?
Of the 139 reports, 103 (74.1%) resulted in death, 96 (69.1%) required hospitalization, and 19 (13.7%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 139 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which PACLITAXEL Alternatives Have Lower Acute hepatic failure Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON