Does LAMOTRIGINE Cause Acute hepatic failure? 108 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 108 reports of Acute hepatic failure have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.2% of all adverse event reports for LAMOTRIGINE.
108
Reports of Acute hepatic failure with LAMOTRIGINE
0.2%
of all LAMOTRIGINE reports
18
Deaths
85
Hospitalizations
How Dangerous Is Acute hepatic failure From LAMOTRIGINE?
Of the 108 reports, 18 (16.7%) resulted in death, 85 (78.7%) required hospitalization, and 28 (25.9%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 108 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which LAMOTRIGINE Alternatives Have Lower Acute hepatic failure Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM