Does METFORMIN Cause Acute hepatic failure? 156 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 156 reports of Acute hepatic failure have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.2% of all adverse event reports for METFORMIN.
156
Reports of Acute hepatic failure with METFORMIN
0.2%
of all METFORMIN reports
61
Deaths
102
Hospitalizations
How Dangerous Is Acute hepatic failure From METFORMIN?
Of the 156 reports, 61 (39.1%) resulted in death, 102 (65.4%) required hospitalization, and 61 (39.1%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 156 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which METFORMIN Alternatives Have Lower Acute hepatic failure Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN