Does ACETAMINOPHEN Cause Liver injury? 3,002 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 3,002 reports of Liver injury have been filed in association with ACETAMINOPHEN (Hydrocodone Bitartrate and Acetaminophen). This represents 2.2% of all adverse event reports for ACETAMINOPHEN.
3,002
Reports of Liver injury with ACETAMINOPHEN
2.2%
of all ACETAMINOPHEN reports
1,473
Deaths
1,992
Hospitalizations
How Dangerous Is Liver injury From ACETAMINOPHEN?
Of the 3,002 reports, 1,473 (49.1%) resulted in death, 1,992 (66.4%) required hospitalization, and 1,635 (54.5%) were considered life-threatening.
Is Liver injury Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ACETAMINOPHEN. However, 3,002 reports have been filed with the FAERS database.
What Other Side Effects Does ACETAMINOPHEN Cause?
Drug ineffective (17,522)
Toxicity to various agents (16,128)
Off label use (9,410)
Vomiting (9,055)
Pain (8,573)
Fatigue (8,202)
Overdose (7,917)
Nausea (7,245)
Rash (7,107)
Headache (7,084)
What Other Drugs Cause Liver injury?
METHOTREXATE (3,601)
RITUXIMAB (2,692)
TOCILIZUMAB (2,637)
ADALIMUMAB (2,635)
PREDNISONE (2,611)
LEFLUNOMIDE (2,574)
ABATACEPT (2,572)
HYDROXYCHLOROQUINE (2,528)
DICLOFENAC (2,487)
SECUKINUMAB (2,441)
Which ACETAMINOPHEN Alternatives Have Lower Liver injury Risk?
ACETAMINOPHEN vs ACETAMINOPHEN AND OR DEXTROMETHORPHAN AND OR DIPHENHYDRAMINE AND OR GUAIFENESIN AND OR PHENYLEPHRINE AND OR PSEUDOEPHEDRINE
ACETAMINOPHEN vs ACETAMINOPHEN W/HYDROCODONE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE
ACETAMINOPHEN vs ACETAMINOPHEN\ASPIRIN\CAFFEINE\SALICYLAMIDE
ACETAMINOPHEN vs ACETAMINOPHEN\BELLADONNA LEAF\CAFFEINE\OPIUM