Does LEFLUNOMIDE Cause Liver injury? 2,574 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,574 reports of Liver injury have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 4.6% of all adverse event reports for LEFLUNOMIDE.
2,574
Reports of Liver injury with LEFLUNOMIDE
4.6%
of all LEFLUNOMIDE reports
1,415
Deaths
1,536
Hospitalizations
How Dangerous Is Liver injury From LEFLUNOMIDE?
Of the 2,574 reports, 1,415 (55.0%) resulted in death, 1,536 (59.7%) required hospitalization, and 1,775 (69.0%) were considered life-threatening.
Is Liver injury Listed in the Official Label?
Yes, Liver injury is listed as a known adverse reaction in the official FDA drug label for LEFLUNOMIDE.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Liver injury?
METHOTREXATE (3,601)
ACETAMINOPHEN (3,002)
RITUXIMAB (2,692)
TOCILIZUMAB (2,637)
ADALIMUMAB (2,635)
PREDNISONE (2,611)
ABATACEPT (2,572)
HYDROXYCHLOROQUINE (2,528)
DICLOFENAC (2,487)
SECUKINUMAB (2,441)
Which LEFLUNOMIDE Alternatives Have Lower Liver injury Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM