Does AFATINIB Cause Stevens-johnson syndrome? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Stevens-johnson syndrome have been filed in association with AFATINIB (Gilotrif). This represents 0.2% of all adverse event reports for AFATINIB.
14
Reports of Stevens-johnson syndrome with AFATINIB
0.2%
of all AFATINIB reports
3
Deaths
11
Hospitalizations
How Dangerous Is Stevens-johnson syndrome From AFATINIB?
Of the 14 reports, 3 (21.4%) resulted in death, 11 (78.6%) required hospitalization, and 4 (28.6%) were considered life-threatening.
Is Stevens-johnson syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AFATINIB. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does AFATINIB Cause?
Diarrhoea (2,001)
Malignant neoplasm progression (1,622)
Rash (808)
Stomatitis (468)
Death (443)
Nausea (430)
Decreased appetite (412)
Vomiting (381)
Paronychia (344)
Dehydration (323)
What Other Drugs Cause Stevens-johnson syndrome?
LAMOTRIGINE (1,384)
ALLOPURINOL (715)
IBUPROFEN (711)
SULFAMETHOXAZOLE\TRIMETHOPRIM (665)
ACETAMINOPHEN (649)
CARBAMAZEPINE (440)
PEMBROLIZUMAB (395)
LEVETIRACETAM (374)
CIPROFLOXACIN (349)
VANCOMYCIN (313)
Which AFATINIB Alternatives Have Lower Stevens-johnson syndrome Risk?
AFATINIB vs AFINITOR
AFATINIB vs AFLIBERCEPT
AFATINIB vs AGALSIDASE ALFA
AFATINIB vs AGALSIDASE BETA
AFATINIB vs AGOMELATINE