AFLIBERCEPT for Prophylaxis: Side Effects & Safety Data
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There are 10 adverse event reports in the FDA FAERS database where AFLIBERCEPT was used for Prophylaxis.
Most Reported Side Effects for AFLIBERCEPT
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 7,669 | 28.5% | 7,666 | 73 |
| Visual impairment | 1,836 | 6.8% | 14 | 167 |
| Blindness | 1,337 | 5.0% | 7 | 134 |
| Endophthalmitis | 1,289 | 4.8% | 5 | 203 |
| Off label use | 1,156 | 4.3% | 115 | 140 |
| Eye pain | 1,057 | 3.9% | 5 | 120 |
| Product dose omission issue | 1,051 | 3.9% | 4 | 40 |
| Blindness unilateral | 1,012 | 3.8% | 11 | 88 |
| Vision blurred | 1,012 | 3.8% | 10 | 97 |
| Visual acuity reduced | 993 | 3.7% | 8 | 89 |
| Blindness transient | 987 | 3.7% | 3 | 30 |
| Drug ineffective | 961 | 3.6% | 18 | 56 |
| Eye inflammation | 875 | 3.3% | 4 | 44 |
| Eye haemorrhage | 739 | 2.8% | 2 | 50 |
| Intraocular pressure increased | 690 | 2.6% | 2 | 33 |
Other Indications for AFLIBERCEPT
Neovascular age-related macular degeneration (8,685)
Product used for unknown indication (6,271)
Diabetic retinal oedema (3,407)
Choroidal neovascularisation (2,953)
Age-related macular degeneration (2,220)
Retinal vein occlusion (1,928)
Diabetic retinopathy (1,720)
Macular oedema (1,362)
Macular degeneration (945)
Colorectal cancer metastatic (915)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)