Does ALENDRONATE Cause Osteonecrosis? 305 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 305 reports of Osteonecrosis have been filed in association with ALENDRONATE (ALENDRONATE SODIUM). This represents 1.1% of all adverse event reports for ALENDRONATE.
305
Reports of Osteonecrosis with ALENDRONATE
1.1%
of all ALENDRONATE reports
4
Deaths
112
Hospitalizations
How Dangerous Is Osteonecrosis From ALENDRONATE?
Of the 305 reports, 4 (1.3%) resulted in death, 112 (36.7%) required hospitalization, and 1 (0.3%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
Yes, Osteonecrosis is listed as a known adverse reaction in the official FDA drug label for ALENDRONATE.
What Other Side Effects Does ALENDRONATE Cause?
Pain (8,989)
Abdominal discomfort (8,301)
Alopecia (8,286)
Systemic lupus erythematosus (8,139)
Fatigue (8,011)
Rheumatoid arthritis (8,010)
Pemphigus (7,947)
Drug ineffective (7,880)
Glossodynia (7,289)
Swelling (6,458)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which ALENDRONATE Alternatives Have Lower Osteonecrosis Risk?
ALENDRONATE vs ALENDRONATE\CHOLECALCIFEROL
ALENDRONATE vs ALENDRONIC ACID
ALENDRONATE vs ALEVE
ALENDRONATE vs ALEVE CAPLET
ALENDRONATE vs ALEVE LIQUID