Does ALLOPURINOL Cause Bone marrow failure? 121 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 121 reports of Bone marrow failure have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.6% of all adverse event reports for ALLOPURINOL.
121
Reports of Bone marrow failure with ALLOPURINOL
0.6%
of all ALLOPURINOL reports
45
Deaths
54
Hospitalizations
How Dangerous Is Bone marrow failure From ALLOPURINOL?
Of the 121 reports, 45 (37.2%) resulted in death, 54 (44.6%) required hospitalization, and 12 (9.9%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 121 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which ALLOPURINOL Alternatives Have Lower Bone marrow failure Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN