Does ALLOPURINOL Cause Constipation? 393 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 393 reports of Constipation have been filed in association with ALLOPURINOL (Allopurinol). This represents 2.1% of all adverse event reports for ALLOPURINOL.
393
Reports of Constipation with ALLOPURINOL
2.1%
of all ALLOPURINOL reports
253
Deaths
207
Hospitalizations
How Dangerous Is Constipation From ALLOPURINOL?
Of the 393 reports, 253 (64.4%) resulted in death, 207 (52.7%) required hospitalization, and 116 (29.5%) were considered life-threatening.
Is Constipation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 393 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which ALLOPURINOL Alternatives Have Lower Constipation Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN