Does ALLOPURINOL Cause Drug hypersensitivity? 450 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 450 reports of Drug hypersensitivity have been filed in association with ALLOPURINOL (Allopurinol). This represents 2.4% of all adverse event reports for ALLOPURINOL.
450
Reports of Drug hypersensitivity with ALLOPURINOL
2.4%
of all ALLOPURINOL reports
148
Deaths
255
Hospitalizations
How Dangerous Is Drug hypersensitivity From ALLOPURINOL?
Of the 450 reports, 148 (32.9%) resulted in death, 255 (56.7%) required hospitalization, and 139 (30.9%) were considered life-threatening.
Is Drug hypersensitivity Listed in the Official Label?
Yes, Drug hypersensitivity is listed as a known adverse reaction in the official FDA drug label for ALLOPURINOL.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Drug hypersensitivity?
METHOTREXATE (16,677)
ETANERCEPT (12,991)
ADALIMUMAB (11,599)
MORPHINE (11,095)
RITUXIMAB (8,924)
LEFLUNOMIDE (8,148)
INFLIXIMAB (8,119)
TOCILIZUMAB (7,883)
ABATACEPT (7,808)
CODEINE (7,479)
Which ALLOPURINOL Alternatives Have Lower Drug hypersensitivity Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN