Does ALLOPURINOL Cause Drug intolerance? 277 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 277 reports of Drug intolerance have been filed in association with ALLOPURINOL (Allopurinol). This represents 1.5% of all adverse event reports for ALLOPURINOL.
277
Reports of Drug intolerance with ALLOPURINOL
1.5%
of all ALLOPURINOL reports
141
Deaths
167
Hospitalizations
How Dangerous Is Drug intolerance From ALLOPURINOL?
Of the 277 reports, 141 (50.9%) resulted in death, 167 (60.3%) required hospitalization, and 128 (46.2%) were considered life-threatening.
Is Drug intolerance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 277 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Drug intolerance?
METHOTREXATE (22,555)
ADALIMUMAB (15,434)
ETANERCEPT (15,146)
LEFLUNOMIDE (14,142)
HYDROXYCHLOROQUINE (14,093)
ABATACEPT (12,451)
TOCILIZUMAB (11,952)
RITUXIMAB (11,876)
SULFASALAZINE (11,530)
INFLIXIMAB (11,173)
Which ALLOPURINOL Alternatives Have Lower Drug intolerance Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN