Does ALLOPURINOL Cause Osteoporosis? 127 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 127 reports of Osteoporosis have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.7% of all adverse event reports for ALLOPURINOL.
127
Reports of Osteoporosis with ALLOPURINOL
0.7%
of all ALLOPURINOL reports
0
Deaths
110
Hospitalizations
How Dangerous Is Osteoporosis From ALLOPURINOL?
Of the 127 reports, 110 (86.6%) required hospitalization, and 54 (42.5%) were considered life-threatening.
Is Osteoporosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 127 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Osteoporosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (7,436)
TENOFOVIR DISOPROXIL (5,302)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,029)
ADALIMUMAB (2,665)
PREDNISONE (2,476)
METHOTREXATE (2,018)
ETANERCEPT (1,766)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (1,720)
TOCILIZUMAB (1,689)
ALENDRONATE (1,688)
Which ALLOPURINOL Alternatives Have Lower Osteoporosis Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN