Does ALLOPURINOL Cause Renal impairment? 424 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 424 reports of Renal impairment have been filed in association with ALLOPURINOL (Allopurinol). This represents 2.2% of all adverse event reports for ALLOPURINOL.
424
Reports of Renal impairment with ALLOPURINOL
2.2%
of all ALLOPURINOL reports
38
Deaths
266
Hospitalizations
How Dangerous Is Renal impairment From ALLOPURINOL?
Of the 424 reports, 38 (9.0%) resulted in death, 266 (62.7%) required hospitalization, and 64 (15.1%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 424 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which ALLOPURINOL Alternatives Have Lower Renal impairment Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN