Does ALLOPURINOL Cause Sinus node dysfunction? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Sinus node dysfunction have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.1% of all adverse event reports for ALLOPURINOL.
11
Reports of Sinus node dysfunction with ALLOPURINOL
0.1%
of all ALLOPURINOL reports
1
Deaths
5
Hospitalizations
How Dangerous Is Sinus node dysfunction From ALLOPURINOL?
Of the 11 reports, 1 (9.1%) resulted in death, 5 (45.5%) required hospitalization, and 1 (9.1%) were considered life-threatening.
Is Sinus node dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Sinus node dysfunction?
AMIODARONE (119)
METOPROLOL (101)
BISOPROLOL (84)
DEXAMETHASONE (69)
APIXABAN (67)
LENALIDOMIDE (66)
LACOSAMIDE (50)
DONEPEZIL (49)
METHOTREXATE (49)
ROSIGLITAZONE (48)
Which ALLOPURINOL Alternatives Have Lower Sinus node dysfunction Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN