Does ALLOPURINOL Cause Skin discolouration? 40 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 40 reports of Skin discolouration have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.2% of all adverse event reports for ALLOPURINOL.
40
Reports of Skin discolouration with ALLOPURINOL
0.2%
of all ALLOPURINOL reports
5
Deaths
26
Hospitalizations
How Dangerous Is Skin discolouration From ALLOPURINOL?
Of the 40 reports, 5 (12.5%) resulted in death, 26 (65.0%) required hospitalization, and 9 (22.5%) were considered life-threatening.
Is Skin discolouration Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 40 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Skin discolouration?
ADAPALENE (2,541)
DUPILUMAB (2,121)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (2,102)
ADALIMUMAB (1,598)
LENALIDOMIDE (1,566)
ETANERCEPT (1,051)
CAPECITABINE (836)
SECUKINUMAB (828)
METHOTREXATE (545)
APIXABAN (391)
Which ALLOPURINOL Alternatives Have Lower Skin discolouration Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN