Skin discolouration: Which Medications Cause It? (34,023 Reports Across 951 Drugs)
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Skin discolouration has been reported as an adverse event with 951 different drugs in the FDA's FAERS database, with 34,023 total reports. 871 of these reports resulted in death.The drugs most commonly associated with Skin discolouration are ADAPALENE, DUPILUMAB, and AVOBENZONE\OCTISALATE\OCTOCRYLENE.
34,023
Total Reports
951
Drugs Involved
871
Deaths
6,123
Hospitalizations
53.0 yrs
Average Patient Age
68.8% / 31.2%
Female / Male
Which Drugs Cause Skin discolouration Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ADAPALENE | 2,541 | 1.4% | 0 | 1 | 1 |
| DUPILUMAB | 2,121 | 0.6% | 5 | 70 | 2 |
| AVOBENZONE\OCTISALATE\OCTOCRYLENE | 2,102 | 1.6% | 0 | 1 | 0 |
| ADALIMUMAB | 1,598 | 0.3% | 31 | 431 | 18 |
| LENALIDOMIDE | 1,566 | 0.5% | 1 | 105 | 1 |
| ETANERCEPT | 1,051 | 0.3% | 5 | 119 | 17 |
| CAPECITABINE | 836 | 1.3% | 21 | 102 | 4 |
| SECUKINUMAB | 828 | 0.6% | 22 | 132 | 25 |
| METHOTREXATE | 545 | 0.2% | 18 | 164 | 37 |
| APIXABAN | 391 | 0.2% | 7 | 94 | 8 |
| IBRUTINIB | 339 | 0.5% | 8 | 108 | 2 |
| PREDNISONE | 329 | 0.2% | 10 | 120 | 11 |
| SUNITINIB MALATE | 318 | 1.5% | 33 | 91 | 4 |
| RUXOLITINIB | 317 | 0.5% | 17 | 75 | 2 |
| RISANKIZUMAB-RZAA | 315 | 0.5% | 2 | 62 | 2 |
| TOFACITINIB | 305 | 0.2% | 1 | 41 | 14 |
| OMALIZUMAB | 296 | 0.5% | 2 | 79 | 13 |
| RIVAROXABAN | 263 | 0.2% | 7 | 49 | 8 |
| COLLAGENASE CLOSTRIDIUM HISTOLYTICUM-AAES | 250 | 21.2% | 0 | 0 | 0 |
| INFLIXIMAB | 240 | 0.2% | 4 | 47 | 5 |