Does METHOTREXATE Cause Skin discolouration? 545 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 545 reports of Skin discolouration have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
545
Reports of Skin discolouration with METHOTREXATE
0.2%
of all METHOTREXATE reports
18
Deaths
164
Hospitalizations
How Dangerous Is Skin discolouration From METHOTREXATE?
Of the 545 reports, 18 (3.3%) resulted in death, 164 (30.1%) required hospitalization, and 37 (6.8%) were considered life-threatening.
Is Skin discolouration Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 545 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Skin discolouration?
ADAPALENE (2,541)
DUPILUMAB (2,121)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (2,102)
ADALIMUMAB (1,598)
LENALIDOMIDE (1,566)
ETANERCEPT (1,051)
CAPECITABINE (836)
SECUKINUMAB (828)
APIXABAN (391)
IBRUTINIB (339)
Which METHOTREXATE Alternatives Have Lower Skin discolouration Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA