Does ALLOPURINOL Cause Skin hyperpigmentation? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Skin hyperpigmentation have been filed in association with ALLOPURINOL (Allopurinol). This represents 0.1% of all adverse event reports for ALLOPURINOL.
9
Reports of Skin hyperpigmentation with ALLOPURINOL
0.1%
of all ALLOPURINOL reports
0
Deaths
8
Hospitalizations
How Dangerous Is Skin hyperpigmentation From ALLOPURINOL?
Of the 9 reports, 8 (88.9%) required hospitalization, and 8 (88.9%) were considered life-threatening.
Is Skin hyperpigmentation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALLOPURINOL. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does ALLOPURINOL Cause?
Drug reaction with eosinophilia and systemic symptoms (2,943)
Acute kidney injury (1,583)
Rash (1,103)
Off label use (921)
Pyrexia (913)
Dyspnoea (905)
Toxic epidermal necrolysis (858)
Pruritus (836)
Diarrhoea (819)
Drug ineffective (780)
What Other Drugs Cause Skin hyperpigmentation?
ADAPALENE (2,811)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (2,277)
BIMATOPROST (189)
AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OXYBENZONE (182)
DUPILUMAB (177)
MINOCYCLINE (144)
LENALIDOMIDE (142)
METHOTREXATE (142)
CAPECITABINE (136)
COLLAGENASE CLOSTRIDIUM HISTOLYTICUM-AAES (120)
Which ALLOPURINOL Alternatives Have Lower Skin hyperpigmentation Risk?
ALLOPURINOL vs ALMOTRIPTAN
ALLOPURINOL vs ALMOTRIPTAN MALATE
ALLOPURINOL vs ALOE VERA LEAF
ALLOPURINOL vs ALOGLIPTIN
ALLOPURINOL vs ALOGLIPTIN\METFORMIN