Does AMPHOTERICIN B Cause Hepatic failure? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Hepatic failure have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.5% of all adverse event reports for AMPHOTERICIN B.
51
Reports of Hepatic failure with AMPHOTERICIN B
0.5%
of all AMPHOTERICIN B reports
33
Deaths
19
Hospitalizations
How Dangerous Is Hepatic failure From AMPHOTERICIN B?
Of the 51 reports, 33 (64.7%) resulted in death, 19 (37.3%) required hospitalization, and 14 (27.5%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 51 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which AMPHOTERICIN B Alternatives Have Lower Hepatic failure Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA