Does AMPHOTERICIN B Cause Skin necrosis? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Skin necrosis have been filed in association with AMPHOTERICIN B (Amphotericin B). This represents 0.3% of all adverse event reports for AMPHOTERICIN B.
27
Reports of Skin necrosis with AMPHOTERICIN B
0.3%
of all AMPHOTERICIN B reports
12
Deaths
19
Hospitalizations
How Dangerous Is Skin necrosis From AMPHOTERICIN B?
Of the 27 reports, 12 (44.4%) resulted in death, 19 (70.4%) required hospitalization, and 20 (74.1%) were considered life-threatening.
Is Skin necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AMPHOTERICIN B. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does AMPHOTERICIN B Cause?
Drug ineffective (4,151)
Off label use (1,529)
Condition aggravated (603)
Acute kidney injury (596)
Multiple organ dysfunction syndrome (465)
Pyrexia (388)
Death (379)
Hypokalaemia (353)
Renal impairment (328)
Septic shock (308)
What Other Drugs Cause Skin necrosis?
METHOTREXATE (620)
ADALIMUMAB (576)
RITUXIMAB (565)
TOCILIZUMAB (530)
ABATACEPT (528)
LEFLUNOMIDE (525)
ETANERCEPT (493)
INFLIXIMAB (491)
HYDROXYCHLOROQUINE (482)
CODEINE (481)
Which AMPHOTERICIN B Alternatives Have Lower Skin necrosis Risk?
AMPHOTERICIN B vs AMPHOTERICIN B\DIMYRISTOYLPHOSPHATIDYLCHOLINE, DL-\DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-
AMPHOTERICIN B vs AMPICILLIN
AMPHOTERICIN B vs AMPICILLIN\SULBACTAM
AMPHOTERICIN B vs AMPRENAVIR
AMPHOTERICIN B vs AMPYRA