Does ANAKINRA Cause Osteonecrosis? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Osteonecrosis have been filed in association with ANAKINRA (Kineret). This represents 0.2% of all adverse event reports for ANAKINRA.
26
Reports of Osteonecrosis with ANAKINRA
0.2%
of all ANAKINRA reports
1
Deaths
1
Hospitalizations
How Dangerous Is Osteonecrosis From ANAKINRA?
Of the 26 reports, 1 (3.8%) resulted in death, 1 (3.8%) required hospitalization, and 1 (3.8%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ANAKINRA. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does ANAKINRA Cause?
Off label use (4,317)
Drug ineffective (3,368)
Pain (1,344)
Condition aggravated (1,339)
Rheumatoid arthritis (1,300)
Drug intolerance (946)
Joint swelling (921)
Injection site pain (879)
Product dose omission issue (864)
Arthralgia (850)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which ANAKINRA Alternatives Have Lower Osteonecrosis Risk?
ANAKINRA vs ANAMORELIN
ANAKINRA vs ANASTROZOLE
ANAKINRA vs ANDEXANET ALFA
ANAKINRA vs ANDROGEL
ANAKINRA vs ANETHOLTRITHION