APREMILAST for Depression: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where APREMILAST was used for Depression.
Most Reported Side Effects for APREMILAST
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 23,752 | 17.4% | 1,249 | 1,695 |
| Nausea | 21,352 | 15.6% | 1,064 | 1,689 |
| Psoriasis | 19,255 | 14.1% | 348 | 882 |
| Headache | 17,024 | 12.5% | 1,240 | 1,645 |
| Drug ineffective | 14,121 | 10.3% | 1,005 | 1,516 |
| Abdominal discomfort | 7,653 | 5.6% | 1,336 | 1,468 |
| Psoriatic arthropathy | 7,035 | 5.2% | 1,594 | 1,778 |
| Vomiting | 5,959 | 4.4% | 1,378 | 1,562 |
| Rash | 5,883 | 4.3% | 1,592 | 1,760 |
| Pain | 5,676 | 4.2% | 1,368 | 1,569 |
| Arthralgia | 5,379 | 3.9% | 1,347 | 1,522 |
| Fatigue | 5,378 | 3.9% | 1,468 | 1,718 |
| Depression | 5,129 | 3.8% | 886 | 914 |
| Weight decreased | 4,692 | 3.4% | 542 | 728 |
| Product dose omission | 4,567 | 3.3% | 0 | 133 |
Other Indications for APREMILAST
Psoriasis (76,127)
Psoriatic arthropathy (33,990)
Product used for unknown indication (27,399)
Rheumatoid arthritis (2,834)
Off label use (1,995)
Behcet's syndrome (752)
Arthritis (389)
Pustular psoriasis (349)
Guttate psoriasis (285)
Palmoplantar pustulosis (226)
Other Drugs Used for Depression
SERTRALINE (14,497)
VENLAFAXINE (11,868)
DULOXETINE (11,681)
ESKETAMINE (10,058)
ESCITALOPRAM OXALATE (7,373)
FLUOXETINE (7,035)
BUPROPION (6,165)
MIRTAZAPINE (6,021)
CITALOPRAM HYDROBROMIDE (5,450)
PAROXETINE (5,386)