BUPROPION for Depression: Side Effects & Safety Data
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There are 6,165 adverse event reports in the FDA FAERS database where BUPROPION was used for Depression.
Most Reported Side Effects for BUPROPION
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Completed suicide | 5,095 | 14.3% | 5,078 | 1,750 |
| Drug ineffective | 3,991 | 11.2% | 157 | 522 |
| Toxicity to various agents | 3,837 | 10.8% | 2,577 | 1,828 |
| Depression | 2,486 | 7.0% | 163 | 374 |
| Overdose | 2,357 | 6.6% | 584 | 1,546 |
| Headache | 2,323 | 6.5% | 119 | 578 |
| Anxiety | 2,145 | 6.0% | 26 | 653 |
| Intentional overdose | 2,103 | 5.9% | 438 | 1,642 |
| Drug hypersensitivity | 1,967 | 5.5% | 110 | 71 |
| Seizure | 1,894 | 5.3% | 231 | 1,285 |
| Fatigue | 1,687 | 4.7% | 137 | 203 |
| Nausea | 1,597 | 4.5% | 37 | 459 |
| Product substitution issue | 1,578 | 4.4% | 0 | 25 |
| Off label use | 1,514 | 4.3% | 141 | 410 |
| Drug interaction | 1,443 | 4.1% | 163 | 617 |
Other Indications for BUPROPION
Product used for unknown indication (18,528)
Anxiety (1,145)
Major depression (988)
Suicide attempt (739)
Bipolar disorder (702)
Smoking cessation therapy (702)
Antidepressant therapy (252)
Attention deficit hyperactivity disorder (244)
Ex-tobacco user (205)
Attention deficit/hyperactivity disorder (192)
Other Drugs Used for Depression
SERTRALINE (14,497)
VENLAFAXINE (11,868)
DULOXETINE (11,681)
ESKETAMINE (10,058)
ESCITALOPRAM OXALATE (7,373)
FLUOXETINE (7,035)
MIRTAZAPINE (6,021)
CITALOPRAM HYDROBROMIDE (5,450)
PAROXETINE (5,386)
VORTIOXETINE HYDROBROMIDE (4,881)