BUPROPION for Major depression: Side Effects & Safety Data

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There are 988 adverse event reports in the FDA FAERS database where BUPROPION was used for Major depression.

Most Reported Side Effects for BUPROPION

Side Effect	Reports	%	Deaths	Hosp.
Completed suicide	5,095	14.3%	5,078	1,750
Drug ineffective	3,991	11.2%	157	522
Toxicity to various agents	3,837	10.8%	2,577	1,828
Depression	2,486	7.0%	163	374
Overdose	2,357	6.6%	584	1,546
Headache	2,323	6.5%	119	578
Anxiety	2,145	6.0%	26	653
Intentional overdose	2,103	5.9%	438	1,642
Drug hypersensitivity	1,967	5.5%	110	71
Seizure	1,894	5.3%	231	1,285
Fatigue	1,687	4.7%	137	203
Nausea	1,597	4.5%	37	459
Product substitution issue	1,578	4.4%	0	25
Off label use	1,514	4.3%	141	410
Drug interaction	1,443	4.1%	163	617