Does APREMILAST Cause Hepatic failure? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Hepatic failure have been filed in association with APREMILAST (Otezla). This represents 0.0% of all adverse event reports for APREMILAST.
26
Reports of Hepatic failure with APREMILAST
0.0%
of all APREMILAST reports
6
Deaths
18
Hospitalizations
How Dangerous Is Hepatic failure From APREMILAST?
Of the 26 reports, 6 (23.1%) resulted in death, 18 (69.2%) required hospitalization, and 1 (3.8%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which APREMILAST Alternatives Have Lower Hepatic failure Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA