Does APREMILAST Cause Knee arthroplasty? 649 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 649 reports of Knee arthroplasty have been filed in association with APREMILAST (Otezla). This represents 0.5% of all adverse event reports for APREMILAST.
649
Reports of Knee arthroplasty with APREMILAST
0.5%
of all APREMILAST reports
480
Deaths
393
Hospitalizations
How Dangerous Is Knee arthroplasty From APREMILAST?
Of the 649 reports, 480 (74.0%) resulted in death, 393 (60.6%) required hospitalization, and 398 (61.3%) were considered life-threatening.
Is Knee arthroplasty Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 649 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Knee arthroplasty?
ADALIMUMAB (3,627)
ETANERCEPT (3,541)
METHOTREXATE (2,311)
ABATACEPT (2,028)
TOCILIZUMAB (1,881)
HYDROXYCHLOROQUINE (1,828)
LEFLUNOMIDE (1,771)
INFLIXIMAB (1,751)
TOFACITINIB (1,744)
CERTOLIZUMAB PEGOL (1,731)
Which APREMILAST Alternatives Have Lower Knee arthroplasty Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA