Does APREMILAST Cause Osteoarthritis? 1,405 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,405 reports of Osteoarthritis have been filed in association with APREMILAST (Otezla). This represents 1.0% of all adverse event reports for APREMILAST.
1,405
Reports of Osteoarthritis with APREMILAST
1.0%
of all APREMILAST reports
1,026
Deaths
864
Hospitalizations
How Dangerous Is Osteoarthritis From APREMILAST?
Of the 1,405 reports, 1,026 (73.0%) resulted in death, 864 (61.5%) required hospitalization, and 839 (59.7%) were considered life-threatening.
Is Osteoarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 1,405 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Osteoarthritis?
ADALIMUMAB (8,893)
METHOTREXATE (4,979)
ETANERCEPT (4,124)
ABATACEPT (3,158)
RITUXIMAB (3,145)
LEFLUNOMIDE (3,131)
TOCILIZUMAB (2,986)
ALENDRONATE (2,851)
TOFACITINIB (2,831)
HYDROXYCHLOROQUINE (2,717)
Which APREMILAST Alternatives Have Lower Osteoarthritis Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA