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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Osteoarthritis: Which Medications Cause It? (30,937 Reports Across 904 Drugs)

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Osteoarthritis has been reported as an adverse event with 904 different drugs in the FDA's FAERS database, with 30,937 total reports. 2,536 of these reports resulted in death.The drugs most commonly associated with Osteoarthritis are ADALIMUMAB, METHOTREXATE, and ETANERCEPT.

30,937
Total Reports
904
Drugs Involved
2,536
Deaths
12,471
Hospitalizations
60.7 yrs
Average Patient Age
76.1% / 23.9%
Female / Male

Which Drugs Cause Osteoarthritis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 8,893 1.8% 1,354 3,952 1,236
METHOTREXATE 4,979 2.0% 1,400 2,524 1,293
ETANERCEPT 4,124 1.2% 1,017 1,840 958
ABATACEPT 3,158 2.7% 1,230 1,861 1,213
RITUXIMAB 3,145 1.8% 1,397 1,990 1,281
LEFLUNOMIDE 3,131 5.5% 1,308 1,703 1,279
TOCILIZUMAB 2,986 3.0% 1,353 1,731 1,124
ALENDRONATE 2,851 10.2% 1,344 2,445 1,193
TOFACITINIB 2,831 1.8% 1,131 1,318 1,036
HYDROXYCHLOROQUINE 2,717 4.1% 1,224 1,649 1,129
SULFASALAZINE 2,601 6.5% 1,246 1,541 1,120
INFLIXIMAB 2,398 1.7% 1,257 1,473 1,162
SECUKINUMAB 2,262 1.5% 1,310 1,518 1,304
PREDNISONE 2,188 1.4% 1,260 1,501 1,195
DICLOFENAC 2,144 2.5% 1,436 1,488 1,301
GOLIMUMAB 1,925 2.8% 1,192 1,262 1,112
CERTOLIZUMAB PEGOL 1,911 1.9% 1,159 1,208 1,052
FOLIC ACID 1,751 7.7% 1,234 1,240 1,144
ETANERCEPT-SZZS 1,647 13.9% 1,163 1,234 1,100
CETIRIZINE 1,576 3.3% 1,257 1,238 1,157

View all 904 drugs →

Top 3 Drugs Associated With Osteoarthritis

8,893 reports
4,979 reports
4,124 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)