Does SULFASALAZINE Cause Osteoarthritis? 2,601 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,601 reports of Osteoarthritis have been filed in association with SULFASALAZINE (Azulfidine EN-tabs). This represents 6.5% of all adverse event reports for SULFASALAZINE.
2,601
Reports of Osteoarthritis with SULFASALAZINE
6.5%
of all SULFASALAZINE reports
1,246
Deaths
1,541
Hospitalizations
How Dangerous Is Osteoarthritis From SULFASALAZINE?
Of the 2,601 reports, 1,246 (47.9%) resulted in death, 1,541 (59.2%) required hospitalization, and 1,120 (43.1%) were considered life-threatening.
Is Osteoarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SULFASALAZINE. However, 2,601 reports have been filed with the FAERS database.
What Other Side Effects Does SULFASALAZINE Cause?
Drug ineffective (22,365)
Rheumatoid arthritis (15,136)
Drug intolerance (11,530)
Pain (11,309)
Fatigue (9,684)
Joint swelling (9,673)
Rash (8,739)
Contraindicated product administered (8,698)
Arthralgia (8,527)
Abdominal discomfort (8,404)
What Other Drugs Cause Osteoarthritis?
ADALIMUMAB (8,893)
METHOTREXATE (4,979)
ETANERCEPT (4,124)
ABATACEPT (3,158)
RITUXIMAB (3,145)
LEFLUNOMIDE (3,131)
TOCILIZUMAB (2,986)
ALENDRONATE (2,851)
TOFACITINIB (2,831)
HYDROXYCHLOROQUINE (2,717)
Which SULFASALAZINE Alternatives Have Lower Osteoarthritis Risk?
SULFASALAZINE vs SULFATHIAZOLE
SULFASALAZINE vs SULFISOMIDINE
SULFASALAZINE vs SULFUR
SULFASALAZINE vs SULFUR HEXAFLUORIDE
SULFASALAZINE vs SULINDAC