Does TOFACITINIB Cause Osteoarthritis? 2,831 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,831 reports of Osteoarthritis have been filed in association with TOFACITINIB (XELJANZ XR). This represents 1.8% of all adverse event reports for TOFACITINIB.
2,831
Reports of Osteoarthritis with TOFACITINIB
1.8%
of all TOFACITINIB reports
1,131
Deaths
1,318
Hospitalizations
How Dangerous Is Osteoarthritis From TOFACITINIB?
Of the 2,831 reports, 1,131 (40.0%) resulted in death, 1,318 (46.6%) required hospitalization, and 1,036 (36.6%) were considered life-threatening.
Is Osteoarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TOFACITINIB. However, 2,831 reports have been filed with the FAERS database.
What Other Side Effects Does TOFACITINIB Cause?
Drug ineffective (30,382)
Pain (21,659)
Condition aggravated (16,925)
Arthralgia (15,640)
Fatigue (13,551)
Rheumatoid arthritis (12,277)
Off label use (11,736)
Headache (11,061)
Joint swelling (10,686)
Malaise (9,040)
What Other Drugs Cause Osteoarthritis?
ADALIMUMAB (8,893)
METHOTREXATE (4,979)
ETANERCEPT (4,124)
ABATACEPT (3,158)
RITUXIMAB (3,145)
LEFLUNOMIDE (3,131)
TOCILIZUMAB (2,986)
ALENDRONATE (2,851)
HYDROXYCHLOROQUINE (2,717)
SULFASALAZINE (2,601)
Which TOFACITINIB Alternatives Have Lower Osteoarthritis Risk?
TOFACITINIB vs TOFERSEN
TOFACITINIB vs TOLNAFTATE
TOFACITINIB vs TOLODODEKIN ALFA
TOFACITINIB vs TOLTERODINE
TOFACITINIB vs TOLVAPTAN