ASPARAGINASE for B precursor type acute leukaemia: Side Effects & Safety Data
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There are 214 adverse event reports in the FDA FAERS database where ASPARAGINASE was used for B precursor type acute leukaemia.
Most Reported Side Effects for ASPARAGINASE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 557 | 11.2% | 96 | 270 |
| Neutropenia | 322 | 6.5% | 50 | 130 |
| Bacterial infection | 295 | 5.9% | 255 | 10 |
| Off label use | 267 | 5.4% | 118 | 88 |
| Secondary immunodeficiency | 233 | 4.7% | 212 | 3 |
| Viral infection | 228 | 4.6% | 228 | 3 |
| Clostridium difficile colitis | 213 | 4.3% | 201 | 16 |
| Pyrexia | 204 | 4.1% | 39 | 123 |
| Sepsis | 200 | 4.0% | 95 | 70 |
| Pneumonia | 196 | 3.9% | 143 | 41 |
| Posterior reversible encephalopathy syndrome | 195 | 3.9% | 4 | 63 |
| Bronchopulmonary aspergillosis | 194 | 3.9% | 163 | 11 |
| Drug ineffective | 192 | 3.9% | 72 | 59 |
| Mycobacterium chelonae infection | 170 | 3.4% | 170 | 1 |
| Death | 169 | 3.4% | 169 | 10 |
Other Indications for ASPARAGINASE
Acute lymphocytic leukaemia (2,690)
T-cell type acute leukaemia (282)
Product used for unknown indication (278)
B-cell type acute leukaemia (207)
Angiocentric lymphoma (148)
Non-hodgkin's lymphoma (135)
Precursor t-lymphoblastic lymphoma/leukaemia (118)
Chemotherapy (98)
Acute myeloid leukaemia (68)
Acute lymphocytic leukaemia recurrent (61)
Other Drugs Used for B precursor type acute leukaemia
BLINATUMOMAB (1,791)
METHOTREXATE (1,067)
VINCRISTINE (977)
DEXAMETHASONE (662)
CYTARABINE (644)
CYCLOPHOSPHAMIDE (598)
PEGASPARGASE (531)
MERCAPTOPURINE (484)
DOXORUBICIN (331)
DAUNORUBICIN (274)