Does ASPIRIN Cause Osteonecrosis? 52 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 52 reports of Osteonecrosis have been filed in association with ASPIRIN (Aspirin). This represents 0.1% of all adverse event reports for ASPIRIN.
52
Reports of Osteonecrosis with ASPIRIN
0.1%
of all ASPIRIN reports
13
Deaths
22
Hospitalizations
How Dangerous Is Osteonecrosis From ASPIRIN?
Of the 52 reports, 13 (25.0%) resulted in death, 22 (42.3%) required hospitalization, and 3 (5.8%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ASPIRIN. However, 52 reports have been filed with the FAERS database.
What Other Side Effects Does ASPIRIN Cause?
Gastrointestinal haemorrhage (13,172)
Anaemia (4,568)
Off label use (4,283)
Dyspnoea (4,280)
Drug hypersensitivity (4,072)
Drug ineffective (4,061)
Upper gastrointestinal haemorrhage (3,411)
Epistaxis (3,214)
Rectal haemorrhage (3,057)
Acute kidney injury (2,976)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which ASPIRIN Alternatives Have Lower Osteonecrosis Risk?
ASPIRIN vs ASPIRIN DL-LYSINE
ASPIRIN vs ASPIRIN LYSINE
ASPIRIN vs ASPIRIN\BUTALBITAL\CAFFEINE
ASPIRIN vs ASPIRIN\CAFFEINE
ASPIRIN vs ASPIRIN\CARISOPRODOL