Does AVACOPAN Cause Hepatic failure? 8 Reports in FDA Database

Q: Does AVACOPAN cause Hepatic failure?

8 reports of Hepatic failure have been filed with the FDA for AVACOPAN, representing 0.2% of all AVACOPAN adverse event reports.

Q: How dangerous is Hepatic failure from AVACOPAN?

Of 8 reports, 3 (37.5%) resulted in death and 5 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Hepatic failure have been filed in association with AVACOPAN (TAVNEOS). This represents 0.2% of all adverse event reports for AVACOPAN.

Reports of Hepatic failure with AVACOPAN

0.2%

of all AVACOPAN reports

Deaths

Hospitalizations

How Dangerous Is Hepatic failure From AVACOPAN?

Of the 8 reports, 3 (37.5%) resulted in death, 5 (62.5%) required hospitalization, and 3 (37.5%) were considered life-threatening.

Is Hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for AVACOPAN. However, 8 reports have been filed with the FAERS database.

What Other Side Effects Does AVACOPAN Cause?

Hospitalisation (520) Off label use (264) Death (254) Fatigue (214) Diarrhoea (211) Nausea (200) Headache (149) Product dose omission issue (145) Pneumonia (143) Covid-19 (139)

What Other Drugs Cause Hepatic failure?

ACETAMINOPHEN (1,392) RIBAVIRIN (888) CYCLOPHOSPHAMIDE (629) METHOTREXATE (598) BEVACIZUMAB (558) SOFOSBUVIR (525) RITUXIMAB (513) VINCRISTINE (468) DOXORUBICIN (462) PREDNISOLONE (425)

Which AVACOPAN Alternatives Have Lower Hepatic failure Risk?

AVACOPAN vs AVALGLUCOSIDASE ALFA-NGPT AVACOPAN vs AVANAFIL AVACOPAN vs AVANDAMET AVACOPAN vs AVANDIA AVACOPAN vs AVAPRITINIB

AVACOPAN Full Profile All Hepatic failure Reports All Drugs Causing Hepatic failure AVACOPAN Demographics