Does AVELUMAB Cause Hepatic failure? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hepatic failure have been filed in association with AVELUMAB (BAVENCIO). This represents 0.4% of all adverse event reports for AVELUMAB.
14
Reports of Hepatic failure with AVELUMAB
0.4%
of all AVELUMAB reports
13
Deaths
6
Hospitalizations
How Dangerous Is Hepatic failure From AVELUMAB?
Of the 14 reports, 13 (92.9%) resulted in death, 6 (42.9%) required hospitalization, and 2 (14.3%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AVELUMAB. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does AVELUMAB Cause?
Death (361)
Disease progression (355)
Off label use (200)
Diarrhoea (153)
Infusion related reaction (142)
Pyrexia (129)
Fatigue (124)
Neoplasm progression (119)
Dyspnoea (100)
Nausea (99)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which AVELUMAB Alternatives Have Lower Hepatic failure Risk?
AVELUMAB vs AVIBACTAM
AVELUMAB vs AVIBACTAM\CEFTAZIDIME
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OCTOCRYLENE\OXYBENZONE\TITANIUM DIOXIDE\ZINC
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OXYBENZONE
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTISALATE\OCTOCRYLENE