Does AVELUMAB Cause Hypophysitis? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Hypophysitis have been filed in association with AVELUMAB (BAVENCIO). This represents 0.4% of all adverse event reports for AVELUMAB.
15
Reports of Hypophysitis with AVELUMAB
0.4%
of all AVELUMAB reports
4
Deaths
3
Hospitalizations
How Dangerous Is Hypophysitis From AVELUMAB?
Of the 15 reports, 4 (26.7%) resulted in death, 3 (20.0%) required hospitalization.
Is Hypophysitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AVELUMAB. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does AVELUMAB Cause?
Death (361)
Disease progression (355)
Off label use (200)
Diarrhoea (153)
Infusion related reaction (142)
Pyrexia (129)
Fatigue (124)
Neoplasm progression (119)
Dyspnoea (100)
Nausea (99)
What Other Drugs Cause Hypophysitis?
IPILIMUMAB (981)
NIVOLUMAB (755)
PEMBROLIZUMAB (411)
CARBOPLATIN (144)
ATEZOLIZUMAB (125)
PACLITAXEL (110)
BEVACIZUMAB (61)
DURVALUMAB (60)
PEMETREXED (51)
CYCLOPHOSPHAMIDE (38)
Which AVELUMAB Alternatives Have Lower Hypophysitis Risk?
AVELUMAB vs AVIBACTAM
AVELUMAB vs AVIBACTAM\CEFTAZIDIME
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OCTOCRYLENE\OXYBENZONE\TITANIUM DIOXIDE\ZINC
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTINOXATE\OCTISALATE\OXYBENZONE
AVELUMAB vs AVOBENZONE\HOMOSALATE\OCTISALATE\OCTOCRYLENE