Does AZACITIDINE Cause Aplasia? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Aplasia have been filed in association with AZACITIDINE (Azacitidine). This represents 0.2% of all adverse event reports for AZACITIDINE.
32
Reports of Aplasia with AZACITIDINE
0.2%
of all AZACITIDINE reports
20
Deaths
15
Hospitalizations
How Dangerous Is Aplasia From AZACITIDINE?
Of the 32 reports, 20 (62.5%) resulted in death, 15 (46.9%) required hospitalization, and 5 (15.6%) were considered life-threatening.
Is Aplasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AZACITIDINE. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does AZACITIDINE Cause?
Febrile neutropenia (2,172)
Death (1,853)
Pneumonia (1,315)
Neutropenia (1,176)
Acute myeloid leukaemia (1,156)
Off label use (1,064)
Pyrexia (1,011)
Thrombocytopenia (968)
Myelosuppression (952)
Anaemia (857)
What Other Drugs Cause Aplasia?
CYTARABINE (229)
ETOPOSIDE (217)
CYCLOPHOSPHAMIDE (213)
METHOTREXATE (199)
VINCRISTINE (167)
DOXORUBICIN (144)
CARBOPLATIN (136)
DEXAMETHASONE (129)
RITUXIMAB (98)
IFOSFAMIDE (88)
Which AZACITIDINE Alternatives Have Lower Aplasia Risk?
AZACITIDINE vs AZATHIOPRINE
AZACITIDINE vs AZD-1222
AZACITIDINE vs AZELAIC ACID
AZACITIDINE vs AZELASTINE
AZACITIDINE vs AZELASTINE\FLUTICASONE