Does AZACITIDINE Cause Osteonecrosis? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Osteonecrosis have been filed in association with AZACITIDINE (Azacitidine). This represents 0.1% of all adverse event reports for AZACITIDINE.
9
Reports of Osteonecrosis with AZACITIDINE
0.1%
of all AZACITIDINE reports
0
Deaths
4
Hospitalizations
How Dangerous Is Osteonecrosis From AZACITIDINE?
Of the 9 reports, 4 (44.4%) required hospitalization, and 1 (11.1%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AZACITIDINE. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does AZACITIDINE Cause?
Febrile neutropenia (2,172)
Death (1,853)
Pneumonia (1,315)
Neutropenia (1,176)
Acute myeloid leukaemia (1,156)
Off label use (1,064)
Pyrexia (1,011)
Thrombocytopenia (968)
Myelosuppression (952)
Anaemia (857)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which AZACITIDINE Alternatives Have Lower Osteonecrosis Risk?
AZACITIDINE vs AZATHIOPRINE
AZACITIDINE vs AZD-1222
AZACITIDINE vs AZELAIC ACID
AZACITIDINE vs AZELASTINE
AZACITIDINE vs AZELASTINE\FLUTICASONE