Does AZATHIOPRINE Cause Osteonecrosis? 168 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 168 reports of Osteonecrosis have been filed in association with AZATHIOPRINE (AZATHIOPRINE). This represents 0.5% of all adverse event reports for AZATHIOPRINE.
168
Reports of Osteonecrosis with AZATHIOPRINE
0.5%
of all AZATHIOPRINE reports
24
Deaths
64
Hospitalizations
How Dangerous Is Osteonecrosis From AZATHIOPRINE?
Of the 168 reports, 24 (14.3%) resulted in death, 64 (38.1%) required hospitalization, and 34 (20.2%) were considered life-threatening.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AZATHIOPRINE. However, 168 reports have been filed with the FAERS database.
What Other Side Effects Does AZATHIOPRINE Cause?
Drug ineffective (8,076)
Off label use (5,358)
Drug intolerance (3,392)
Condition aggravated (2,832)
Rheumatoid arthritis (2,746)
Treatment failure (2,483)
Arthralgia (2,427)
Drug hypersensitivity (2,421)
Nausea (2,178)
Pneumonia (2,157)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which AZATHIOPRINE Alternatives Have Lower Osteonecrosis Risk?
AZATHIOPRINE vs AZD-1222
AZATHIOPRINE vs AZELAIC ACID
AZATHIOPRINE vs AZELASTINE
AZATHIOPRINE vs AZELASTINE\FLUTICASONE
AZATHIOPRINE vs AZELNIDIPINE