Does BEVACIZUMAB Cause Large intestine perforation? 406 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 406 reports of Large intestine perforation have been filed in association with BEVACIZUMAB (JOBEVNE). This represents 0.5% of all adverse event reports for BEVACIZUMAB.
406
Reports of Large intestine perforation with BEVACIZUMAB
0.5%
of all BEVACIZUMAB reports
148
Deaths
264
Hospitalizations
How Dangerous Is Large intestine perforation From BEVACIZUMAB?
Of the 406 reports, 148 (36.5%) resulted in death, 264 (65.0%) required hospitalization, and 83 (20.4%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BEVACIZUMAB. However, 406 reports have been filed with the FAERS database.
What Other Side Effects Does BEVACIZUMAB Cause?
Off label use (12,094)
Death (8,493)
Diarrhoea (4,911)
Disease progression (4,653)
Fatigue (4,572)
Nausea (4,357)
Hypertension (4,309)
Anaemia (3,221)
Vomiting (3,193)
Neutropenia (2,875)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
TOCILIZUMAB (154)
Which BEVACIZUMAB Alternatives Have Lower Large intestine perforation Risk?
BEVACIZUMAB vs BEVACIZUMAB-AWWB
BEVACIZUMAB vs BEVACIZUMAB-BVZR
BEVACIZUMAB vs BEVACIZUMAB-MALY
BEVACIZUMAB vs BEXAROTENE
BEVACIZUMAB vs BEYAZ