Does FLUOROURACIL Cause Large intestine perforation? 162 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 162 reports of Large intestine perforation have been filed in association with FLUOROURACIL (FLUOROURACIL). This represents 0.3% of all adverse event reports for FLUOROURACIL.
162
Reports of Large intestine perforation with FLUOROURACIL
0.3%
of all FLUOROURACIL reports
54
Deaths
132
Hospitalizations
How Dangerous Is Large intestine perforation From FLUOROURACIL?
Of the 162 reports, 54 (33.3%) resulted in death, 132 (81.5%) required hospitalization, and 38 (23.5%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FLUOROURACIL. However, 162 reports have been filed with the FAERS database.
What Other Side Effects Does FLUOROURACIL Cause?
Diarrhoea (5,373)
Neutropenia (4,400)
Nausea (3,757)
Vomiting (2,836)
Off label use (2,788)
Neuropathy peripheral (2,605)
Thrombocytopenia (2,426)
Fatigue (2,421)
Disease progression (2,377)
Febrile neutropenia (2,230)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
PEMBROLIZUMAB (157)
TOCILIZUMAB (154)
Which FLUOROURACIL Alternatives Have Lower Large intestine perforation Risk?
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN
FLUOROURACIL vs FLUOROURACIL\IRINOTECAN\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOROURACIL\LEUCOVORIN\OXALIPLATIN
FLUOROURACIL vs FLUOXETINE
FLUOROURACIL vs FLUOXETINE\FLUOXETINE