Does PACLITAXEL Cause Large intestine perforation? 191 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 191 reports of Large intestine perforation have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.3% of all adverse event reports for PACLITAXEL.
191
Reports of Large intestine perforation with PACLITAXEL
0.3%
of all PACLITAXEL reports
68
Deaths
114
Hospitalizations
How Dangerous Is Large intestine perforation From PACLITAXEL?
Of the 191 reports, 68 (35.6%) resulted in death, 114 (59.7%) required hospitalization, and 33 (17.3%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 191 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
TOCILIZUMAB (154)
Which PACLITAXEL Alternatives Have Lower Large intestine perforation Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON