Does BINIMETINIB Cause Immune-mediated enterocolitis? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Immune-mediated enterocolitis have been filed in association with BINIMETINIB (MEKTOVI). This represents 0.3% of all adverse event reports for BINIMETINIB.
18
Reports of Immune-mediated enterocolitis with BINIMETINIB
0.3%
of all BINIMETINIB reports
5
Deaths
13
Hospitalizations
How Dangerous Is Immune-mediated enterocolitis From BINIMETINIB?
Of the 18 reports, 5 (27.8%) resulted in death, 13 (72.2%) required hospitalization, and 1 (5.6%) were considered life-threatening.
Is Immune-mediated enterocolitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BINIMETINIB. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does BINIMETINIB Cause?
Off label use (902)
Death (719)
Nausea (657)
Fatigue (562)
Diarrhoea (521)
Product use in unapproved indication (508)
Pyrexia (490)
Neoplasm progression (387)
Vomiting (375)
Rash (360)
What Other Drugs Cause Immune-mediated enterocolitis?
NIVOLUMAB (1,289)
IPILIMUMAB (988)
PEMBROLIZUMAB (858)
CARBOPLATIN (307)
PACLITAXEL (188)
DURVALUMAB (165)
ATEZOLIZUMAB (156)
LENVATINIB (143)
PEMETREXED (129)
BEVACIZUMAB (92)
Which BINIMETINIB Alternatives Have Lower Immune-mediated enterocolitis Risk?
BINIMETINIB vs BIOFLAVONOIDS
BINIMETINIB vs BIOTIN
BINIMETINIB vs BIPERIDEN
BINIMETINIB vs BIRCH TRITERPENES
BINIMETINIB vs BISACODYL