Does BINIMETINIB Cause Renal impairment? 90 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 90 reports of Renal impairment have been filed in association with BINIMETINIB (MEKTOVI). This represents 1.3% of all adverse event reports for BINIMETINIB.
90
Reports of Renal impairment with BINIMETINIB
1.3%
of all BINIMETINIB reports
6
Deaths
44
Hospitalizations
How Dangerous Is Renal impairment From BINIMETINIB?
Of the 90 reports, 6 (6.7%) resulted in death, 44 (48.9%) required hospitalization, and 6 (6.7%) were considered life-threatening.
Is Renal impairment Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BINIMETINIB. However, 90 reports have been filed with the FAERS database.
What Other Side Effects Does BINIMETINIB Cause?
Off label use (902)
Death (719)
Nausea (657)
Fatigue (562)
Diarrhoea (521)
Product use in unapproved indication (508)
Pyrexia (490)
Neoplasm progression (387)
Vomiting (375)
Rash (360)
What Other Drugs Cause Renal impairment?
LENALIDOMIDE (2,161)
EMTRICITABINE\TENOFOVIR DISOPROXIL (2,128)
TACROLIMUS (2,124)
OMEPRAZOLE (2,075)
LANSOPRAZOLE (2,063)
METHOTREXATE (1,852)
ESOMEPRAZOLE (1,811)
PANTOPRAZOLE (1,713)
SACUBITRIL\VALSARTAN (1,610)
CYCLOSPORINE (1,489)
Which BINIMETINIB Alternatives Have Lower Renal impairment Risk?
BINIMETINIB vs BIOFLAVONOIDS
BINIMETINIB vs BIOTIN
BINIMETINIB vs BIPERIDEN
BINIMETINIB vs BIRCH TRITERPENES
BINIMETINIB vs BISACODYL