Does BORTEZOMIB Cause Osteonecrosis? 28 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Osteonecrosis have been filed in association with BORTEZOMIB (bortezomib). This represents 0.1% of all adverse event reports for BORTEZOMIB.
28
Reports of Osteonecrosis with BORTEZOMIB
0.1%
of all BORTEZOMIB reports
2
Deaths
7
Hospitalizations
How Dangerous Is Osteonecrosis From BORTEZOMIB?
Of the 28 reports, 2 (7.1%) resulted in death, 7 (25.0%) required hospitalization.
Is Osteonecrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BORTEZOMIB. However, 28 reports have been filed with the FAERS database.
What Other Side Effects Does BORTEZOMIB Cause?
Plasma cell myeloma (6,683)
Off label use (4,754)
Neuropathy peripheral (4,067)
Drug ineffective (2,730)
Diarrhoea (2,244)
Thrombocytopenia (2,082)
Death (2,025)
Pneumonia (2,020)
Fatigue (1,757)
Neutropenia (1,530)
What Other Drugs Cause Osteonecrosis?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,935)
TENOFOVIR DISOPROXIL (7,182)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,338)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,081)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,492)
PREDNISONE (779)
PREDNISOLONE (711)
DENOSUMAB (567)
METHOTREXATE (563)
DEXAMETHASONE (531)
Which BORTEZOMIB Alternatives Have Lower Osteonecrosis Risk?
BORTEZOMIB vs BOSENTAN
BORTEZOMIB vs BOSENTAN\BOSENTAN
BORTEZOMIB vs BOSULIF
BORTEZOMIB vs BOSUTINIB
BORTEZOMIB vs BOTOX