Does BUPIVACAINE Cause Depression? 60 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 60 reports of Depression have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 0.5% of all adverse event reports for BUPIVACAINE.
60
Reports of Depression with BUPIVACAINE
0.5%
of all BUPIVACAINE reports
12
Deaths
30
Hospitalizations
How Dangerous Is Depression From BUPIVACAINE?
Of the 60 reports, 12 (20.0%) resulted in death, 30 (50.0%) required hospitalization, and 24 (40.0%) were considered life-threatening.
Is Depression Listed in the Official Label?
Yes, Depression is listed as a known adverse reaction in the official FDA drug label for BUPIVACAINE.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Depression?
OXYCODONE (6,871)
ADALIMUMAB (6,340)
APREMILAST (5,129)
ACETAMINOPHEN\OXYCODONE (4,035)
ACETAMINOPHEN\HYDROCODONE (3,699)
METHOTREXATE (3,577)
ETANERCEPT (3,538)
LEVONORGESTREL (3,529)
MORPHINE (3,280)
PREDNISONE (3,211)
Which BUPIVACAINE Alternatives Have Lower Depression Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE