Does BUPRENORPHINE Cause Synovitis? 540 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 540 reports of Synovitis have been filed in association with BUPRENORPHINE (Buprenorphine and Naloxone). This represents 0.7% of all adverse event reports for BUPRENORPHINE.
540
Reports of Synovitis with BUPRENORPHINE
0.7%
of all BUPRENORPHINE reports
536
Deaths
468
Hospitalizations
How Dangerous Is Synovitis From BUPRENORPHINE?
Of the 540 reports, 536 (99.3%) resulted in death, 468 (86.7%) required hospitalization, and 473 (87.6%) were considered life-threatening.
Is Synovitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPRENORPHINE. However, 540 reports have been filed with the FAERS database.
What Other Side Effects Does BUPRENORPHINE Cause?
Drug dependence (16,730)
Overdose (13,977)
Death (13,604)
Toxicity to various agents (10,906)
Pain (8,219)
Drug withdrawal syndrome (7,149)
Emotional distress (6,159)
Drug abuse (4,344)
Drug ineffective (4,261)
Dependence (3,184)
What Other Drugs Cause Synovitis?
METHOTREXATE (11,451)
ADALIMUMAB (9,965)
ABATACEPT (9,783)
ETANERCEPT (9,599)
TOCILIZUMAB (9,428)
HYDROXYCHLOROQUINE (9,123)
LEFLUNOMIDE (8,889)
RITUXIMAB (7,956)
INFLIXIMAB (7,856)
SULFASALAZINE (7,566)
Which BUPRENORPHINE Alternatives Have Lower Synovitis Risk?
BUPRENORPHINE vs BUPRENORPHINE\NALOXONE
BUPRENORPHINE vs BUPROPION
BUPRENORPHINE vs BUPROPION HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\NALTREXONE