Does BUSULFAN Cause Adrenal insufficiency? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Adrenal insufficiency have been filed in association with BUSULFAN (Busulfan). This represents 0.1% of all adverse event reports for BUSULFAN.
15
Reports of Adrenal insufficiency with BUSULFAN
0.1%
of all BUSULFAN reports
2
Deaths
3
Hospitalizations
How Dangerous Is Adrenal insufficiency From BUSULFAN?
Of the 15 reports, 2 (13.3%) resulted in death, 3 (20.0%) required hospitalization, and 3 (20.0%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUSULFAN. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does BUSULFAN Cause?
Off label use (1,402)
Product use in unapproved indication (1,387)
Mucosal inflammation (880)
Venoocclusive liver disease (765)
Febrile neutropenia (628)
Cytomegalovirus infection (620)
Drug ineffective (569)
Graft versus host disease (507)
Pyrexia (502)
Cytomegalovirus infection reactivation (481)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which BUSULFAN Alternatives Have Lower Adrenal insufficiency Risk?
BUSULFAN vs BUSULFEX
BUSULFAN vs BUTALBITAL
BUSULFAN vs BUTENAFINE
BUSULFAN vs BUTORPHANOL
BUSULFAN vs BUTRANS